Digital PCR & Quantification Platforms for Ultra-Precise Molecular Measurement
Achieve ultra-sensitive and reproducible molecular quantification with digital PCR technologies engineered for precision and speed.
Absolute Measurement Redefined
Digital PCR & Quantification Platforms bring a transformative level of sensitivity and precision to molecular measurement workflows. Unlike traditional qPCR, digital PCR (dPCR) offers absolute quantification by partitioning samples into thousands of individual reactions—enabling detection of rare variants, accurate copy number analysis, and ultra-sensitive gene expression studies. These platforms have become essential for clinical diagnostics, precision medicine, infectious disease detection, and gene therapy validation.
Through microfluidics, droplet generation, advanced thermal cycling, and cloud-integrated software, Bioinformatics Digital offers tools that maximize data reliability, reproducibility, and throughput. Built for B2B laboratories and life sciences companies across North America, our solutions help organizations streamline workflows, minimize errors, and unlock next-level precision in molecular testing.
With scalable systems, compliance-ready features, and world-class support, Bioinformatics Digital is redefining quantification for modern laboratories.
Core Technology & Components
In addition to offering internally developed digital PCR tools and platforms, BioinformaticsDigital proudly partners with Global Advanced Operations Tek Inc. (GAO Tek Inc.) and Global Advanced Operations RFID Inc. (GAO RFID Inc.) to expand access to robust,
validated technologies. These systems are integrated into our infrastructure for enhanced functionality and enterprise-scale implementation.
Hardware
Droplet-Based Digital PCR (ddPCR) Systems
Advanced dPCR platforms using microfluidic droplet partitioning to isolate single DNA molecules, enabling absolute quantification with attomolar sensitivity.
Chip-Based Parallel Well dPCR Systems
Compact, chip-based digital PCR instruments featuring parallel well arrays for high-throughput reactions and multiplexed gene target analysis.
Software & Automation
Copy number quantification and mutation frequency analysis tools
Absolute quantification without calibration curves
Real-time result interpretation with statistical confidence scoring
LIMS-compatible data export with 21 CFR Part 11 audit trail tracking
Infrastructure & Connectivity
- Edge-compute systems for on-site, high-throughput PCR runs
- API-integrated data transfer to bioinformatics pipelines
- Secure data storage solutions aligned with HIPAA and GDPR
- AI modules for automated assay quality assurance and drift detection
Real-World Applications
- Liquid biopsy analysis for cancer and prenatal diagnostics
- Viral load quantification in infectious disease surveillance
- Gene therapy validation and vector copy number analysis
- GMO testing and trait quantification in agricultural genomics
- Rare mutation detection in oncology, neurology, and immunology
Benefits of Choosing Bioinformatics Digital
- Boost quantification accuracy with single-molecule resolution
- Eliminate standard curve variability in molecular assays
- Streamline workflows with automated system components
- Integrate digital PCR data into broader omics pipelines
- Ensure compliance with HIPAA, FDA, and Health Canada regulations
- Leverage our expert support, scalable infrastructure, and industry-driven development
Integrations & Compatibility
Laboratory Systems
LIMS, ELN, and clinical diagnostics databases
Informatics Integration
R, Python, Bioconductor workflows
Sample Types
Genomic DNA, cDNA, RNA, plasmid DNA, viral templates
Assay Compatibility
TaqMan, EvaGreen, hydrolysis probes
Key Features & Functionalities
- Absolute quantification of DNA/RNA targets
- Single-copy sensitivity for low-abundance mutations
- Multiplexing capabilities with fluorescent probe libraries
- Real-time and endpoint quantification modes
- Automated sample partitioning and droplet stability control
- High-throughput formats for diagnostic or research workflows
Industry Use Cases
- Clinical diagnostic laboratories
- Biotechnology manufacturing QC units
- Environmental testing organizations
- Agricultural genomics research labs
- Academic institutions specializing in molecular biology
Applicable Standards & Regulations (U.S. & Canada)
- FDA 21 CFR Part 11 (Electronic Records Compliance)
- ISO 15189 for Clinical Laboratory Testing
- HIPAA and GDPR Data Security Standards
- Health Canada Medical Device Regulations
- CLSI MM14-A for Nucleic Acid Quantification
Case Studies
U.S. – Clinical Lab Accelerates Liquid Biopsy Diagnostics
A California-based diagnostic company implemented BioinformaticsDigital’s ddPCR platform for non-invasive cancer monitoring. Turnaround time dropped by 30%, while detection of rare mutations improved by 3x compared to legacy systems.
Canada – Biotech Company Quantifies Gene Therapy Vectors
A Toronto gene therapy firm deployed our chip-based digital PCR system to validate vector copy numbers during manufacturing. It resulted in a 40% increase in QC throughput and enhanced regulatory readiness.
U.S. – Academic Center Uses dPCR to Track COVID-19 Variants
A university public health lab in New York adopted BioinformaticsDigital’s droplet PCR system to quantify emerging SARS-CoV-2 variants with improved accuracy, helping inform local containment policies.
Ready to revolutionize your quantification workflows with cutting-edge digital PCR?
Let’s build precision into your pipeline.
Contact Us for expert guidance, customized platform integration, or product support. Our team is here to help with scalable, compliant, and powerful solutions tailored to your molecular testing needs.
